J'aime pas l'anglais

C'est strictement impossible de cloner totalement un néandertal, lui même l'admet indirectement dans son discours. Il faudra une base humaine, comme il l'explique avec les cellules souches et leur culture, et encore, faudra que ces cellules souches soit totipotente, et donc faudra toucher à des embryons humains... A moins que la technique d'inversion de différenciation du prix nobel 2012 se soit assez avancé d'ici là.
" Church: The first thing you have to do is to sequence the Neanderthal genome, and that has actually been done. The next step would be to chop this genome up into, say, 10,000 chunks and then synthesize these. Finally, you would introduce these chunks into a human stem cell. If we do that often enough, then we would generate a stem cell line that would get closer and closer to the corresponding sequence of the Neanderthal. We developed the semi-automated procedure required to do that in my lab. Finally, we assemble all the chunks in a human stem cell, which would enable you to finally create a Neanderthal clone. "
L'Homme n'a pas encore percé la totalité de l'ADN et veut jouer avec ceux dont on a même pas les parties entières, et le re créer en plus, ça me fait marrer
Décidément, il est un peu trop optimiste ce chercheur
Church:
yes, and the potential of synthetic life is particularly large in pharmaceuticals. The days of classic, small molecule drugs may be numbered. Actually, it is a miracle that they work in the first place. They kind of dose your whole body. They cross-react with other molecules. Now, we are getting better and better at programming cells. So I think cell therapies are going to be the next big thing. If you engineer genomes and cells, you have an incredible amount of sophistication. If you take AIDS virus as an example ...
SPIEGEL: ... a disease you also want to beat with cell therapy?
Church: Yes. All you have to do is take your blood cell precursors out of your body, reengineer them using gene therapy to knock out both copies of your CCR5 gene, which is the AIDS receptor, and then put them back in your body. Then you can't get AIDS any more, because the virus can't enter your cells.
Cela fait juste un bon paquet de temps que les chercheurs s'arrachent les cheveux à chercher à faire ce genre d'élément, mais le Sida mute...
Church: In order to find out, we are now involved in sequencing as many people as possible who have lived for over 110 years. There are only 60 of those people in the world that we know of.
SPIEGEL: Do you have any results already?
Church: It's too early to say. But we collected the DNA of about 20 of them, and the analysis is just beginning.
SPIEGEL: You expect them all to have the same mutation that guarantees longevity?
Church: That is one possibility. The other possibility is that they each have their own little advantage over everybody else. What we are looking for is protective alleles. If they each have their own answer, we can look at all of them and ask, what happens if you put them all in one person? Do they cancel each other out, or do they synergize?
Il va loin, bien loin, une théorie sur le fait que les personnes les plus vieilles viveraient ainsi grâce à une/des mutations sur des allèles protecteurs...